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Using UV-absorbance of intrinsic dithiothreitol (DTT) during RP-HPLC as a measure of experimental redox potential in vitro

Many in vitro experiments aimed at studying the response of thiol-containing proteins to changes in environmental redox potentials use dithiothreitol (DTT) to maintain a preset redox environment throughout the experiments. However, the gradual oxidation of DTT during the course of the experiments, a...

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Detalhes bibliográficos
Main Authors: Seo, Angie, Jackson, Janelle L., Schuster, Jolene V, Vardar-Ulu, Didem
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728560/
https://ncbi.nlm.nih.gov/pubmed/23743664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-013-7063-2
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