Effect of ghrelin and anamorelin (ONO-7643), a selective ghrelin receptor agonist, on tumor growth in a lung cancer mouse xenograft model

PURPOSE: Anamorelin (ONO-7643) is an orally active ghrelin receptor agonist in development for non-small cell lung cancer (NSCLC)-related anorexia/cachexia. It displays both orexigenic and anabolic properties via ghrelin mimetic activity and transient increases in growth hormone (GH). However, incre...

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Hauptverfasser: Northrup, R., Kuroda, K., Duus, E. Manning, Barnes, S. Routt, Cheatham, L., Wiley, T., Pietra, C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2013
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728440/
https://ncbi.nlm.nih.gov/pubmed/23579947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00520-013-1800-0
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