NF-κB Regulates Mesenchymal Transition for the Induction of Non-Small Cell Lung Cancer Initiating Cells

The epithelial-to-mesenchymal transition (EMT) is a de-differentiation process that has been implicated in metastasis and the generation of cancer initiating cells (CICs) in solid tumors. To examine EMT in non-small cell lung cancer (NSCLC), we utilized a three dimensional (3D) cell culture system i...

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Détails bibliographiques
Auteurs principaux: Kumar, Manish, Allison, David F., Baranova, Natalya N., Wamsley, J. Jacob, Katz, Adam J., Bekiranov, Stefan, Jones, David R., Mayo, Marty W.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728367/
https://ncbi.nlm.nih.gov/pubmed/23935876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068597
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