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Herbal compound triptolide synergistically enhanced antitumor activity of amino-terminal fragment of urokinase

BACKGROUND: Urokinase (uPA) and its receptor (uPAR) play an important role in tumour growth and metastasis, and overexpression of these molecules is strongly correlated with poor prognosis in a variety of malignant tumours. Targeting the excessive activation of this system as well as the proliferati...

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Detalhes bibliográficos
Main Authors: Lin, Yuli, Peng, Nana, Li, Jianping, Zhuang, Hongqin, Hua, Zi-Chun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728221/
https://ncbi.nlm.nih.gov/pubmed/23758884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-54
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