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Design and application of a novel PNA probe for the detection at single cell level of JAK2(V617F) mutation in Myeloproliferative Neoplasms
BACKGROUND: Mutation(s) of the JAK2 gene (V617F) has been described in a significant proportion of Philadelphia negative Myeloproliferative Neoplasms (MPN) patients and its detection is now a cornerstone in the diagnostic algorithm. METHODS: We developed a novel assay based on peptide nucleic acid (...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3728119/ https://ncbi.nlm.nih.gov/pubmed/23865766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-348 |
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