Quantification of β-cell insulin secretory function using a graded glucose infusion with C-peptide deconvolution in dysmetabolic, and diabetic cynomolgus monkeys

BACKGROUND: Quantitation of β-cell function is critical in better understanding of the dynamic interactions of insulin secretion, clearance and action at different phases in the progression of diabetes. The present study aimed to quantify β-cell secretory function independently of insulin sensitivit...

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Huvudupphovsmän: Wang, Xiaoli, Hansen, Barbara C, Shi, Da, Fang, Yupeng, Du, Fenglai, Wang, Bingdi, Chen, Yaxiong Michael, Gregoire, Francine M, Wang, Yi-Xin Jim
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2013
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728033/
https://ncbi.nlm.nih.gov/pubmed/23886319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1758-5996-5-40
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