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Quantification of β-cell insulin secretory function using a graded glucose infusion with C-peptide deconvolution in dysmetabolic, and diabetic cynomolgus monkeys

BACKGROUND: Quantitation of β-cell function is critical in better understanding of the dynamic interactions of insulin secretion, clearance and action at different phases in the progression of diabetes. The present study aimed to quantify β-cell secretory function independently of insulin sensitivit...

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Bibliografische gegevens
Hoofdauteurs: Wang, Xiaoli, Hansen, Barbara C, Shi, Da, Fang, Yupeng, Du, Fenglai, Wang, Bingdi, Chen, Yaxiong Michael, Gregoire, Francine M, Wang, Yi-Xin Jim
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728033/
https://ncbi.nlm.nih.gov/pubmed/23886319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1758-5996-5-40
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