Quantification of β-cell insulin secretory function using a graded glucose infusion with C-peptide deconvolution in dysmetabolic, and diabetic cynomolgus monkeys

BACKGROUND: Quantitation of β-cell function is critical in better understanding of the dynamic interactions of insulin secretion, clearance and action at different phases in the progression of diabetes. The present study aimed to quantify β-cell secretory function independently of insulin sensitivit...

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Главные авторы: Wang, Xiaoli, Hansen, Barbara C, Shi, Da, Fang, Yupeng, Du, Fenglai, Wang, Bingdi, Chen, Yaxiong Michael, Gregoire, Francine M, Wang, Yi-Xin Jim
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2013
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Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728033/
https://ncbi.nlm.nih.gov/pubmed/23886319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1758-5996-5-40
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