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Functional characterisation of human cells harbouring a novel t(2p;7p) translocation involving TNS3 and EXOC6B genes

BACKGROUND: Tensin3 is an intracellular cytoskeleton-regulating protein, the loss of which is associated with increased cell motility, as has been observed in some human cancers. A novel chromosomal translocation, t(2;7)(p13;p12), present in a patient with a complex syndromic phenotype, directly inv...

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Main Authors: Ludwig, Desiree, Carter, Jessica, Smith, James R, Borsani, Giuseppe, Barlati, Sergio, Hafizi, Sassan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728010/
https://ncbi.nlm.nih.gov/pubmed/23809228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-14-65
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