A hexadecylamide derivative of hyaluronan (HYMOVIS®) has superior beneficial effects on human osteoarthritic chondrocytes and synoviocytes than unmodified hyaluronan

BACKGROUND: Intra-articular hyaluronan (HA) injection provides symptomatic benefit in the treatment of osteoarthritis (OA). Previously we found superior beneficial effects in a large animal OA model of a hexadecylamide derivative compared with unmodified HA of the same initial molecular weight. The...

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Detalhes bibliográficos
Main Authors: Smith, Margaret M, Russell, Amy K, Schiavinato, Antonella, Little, Christopher B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727958/
https://ncbi.nlm.nih.gov/pubmed/23889808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-9255-10-26
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