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Differential Regulation of Pulmonary Vascular Cell Growth by Hypoxia-Inducible Transcription Factor–1α and Hypoxia-Inducible Transcription Factor–2α

Hypoxia-inducible transcription factors HIF-1α and HIF-2α can contribute to pulmonary hypertension and vascular remodeling, but their mechanisms remain unknown. This study investigated the role of HIF-1α and HIF-2α in pulmonary artery endothelial and smooth muscle cells. The exposure of human pulmon...

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Autori principali: Ahmad, Aftab, Ahmad, Shama, Malcolm, Kenneth C., Miller, Stacy M., Hendry-Hofer, Tara, Schaack, Jerome B., White, Carl W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727885/
https://ncbi.nlm.nih.gov/pubmed/23492195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0107OC
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