Hyperoxia and Interferon-γ–Induced Injury in Developing Lungs Occur via Cyclooxygenase-2 and the Endoplasmic Reticulum Stress–Dependent Pathway

We noted a marked increase in cyclooxygenase-2 (Cox2) and the activation of the endoplasmic reticulum (ER) stress pathway in newborn murine lung on exposure to hyperoxia and IFN-γ. We sought to evaluate Cox2-mediated ER stress pathway activation in hyperoxia-induced and IFN-γ–mediated injury in deve...

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Hauptverfasser: Choo-Wing, Rayman, Syed, Mansoor A., Harijith, Anantha, Bowen, Brianne, Pryhuber, Gloria, Janér, Cecilia, Andersson, Sture, Homer, Robert J., Bhandari, Vineet
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2013
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727872/
https://ncbi.nlm.nih.gov/pubmed/23470621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0381OC
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