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The role of TGF-β in bone metastasis: novel therapeutic perspectives
The skeleton is a preferred site for cancer metastasis. These bone metastases cause dysregulated bone remodeling and the associated morbidity of fractures, pain, hypercalcemia and catastrophic nerve compression syndromes. Transforming growth factor-β (TGF-β) is stored in mineralized bone matrix, and...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3727840/ https://ncbi.nlm.nih.gov/pubmed/23951484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bonekey.2012.96 |
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