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Wnt Signaling Orchestration with a Small Molecule DYRK Inhibitor Provides Long-Term Xeno-Free Human Pluripotent Cell Expansion

An optimal culture system for human pluripotent stem cells should be fully defined and free of animal components. To date, most xeno-free culture systems require human feeder cells and/or highly complicated culture media that contain activators of the fibroblast growth factor (FGF) and transforming...

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Main Authors: Hasegawa, Kouichi, Yasuda, Shin-ya, Teo, Jia-Ling, Nguyen, Cu, McMillan, Michael, Hsieh, Chih-Lin, Suemori, Hirofumi, Nakatsuji, Norio, Yamamoto, Masashi, Miyabayashi, Tomoyuki, Lutzko, Carolyn, Pera, Martin F., Kahn, Michael
Formato: Artigo
Idioma:Inglês
Publicado: AlphaMed Press 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727690/
https://ncbi.nlm.nih.gov/pubmed/23197636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2011-0033
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