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Mild and convenient N-formylation protocol in water-containing solvents
We have realized that N-formylations of free amines of some drug leads can improve PK/PD property of parent molecules without decreasing their biological activities. In order to selectively formylate primary amines of polyfunctional molecules, we have sought a mild and convenient formylation reactio...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3727664/ https://ncbi.nlm.nih.gov/pubmed/23908559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2013.02.013 |
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