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CD40 ligand is necessary and sufficient to support primary diffuse large B-cell lymphoma cells in culture: a tool for in vitro preclinical studies with primary B-cell malignancies

Established cell lines are utilized extensively to study tumor biology and preclinical therapeutic development; however, they may not accurately recapitulate the heterogeneity of their corresponding primary disease. B-cell tumor cells are especially difficult to maintain under conventional culture c...

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Detalhes bibliográficos
Main Authors: Ito, Daisuke, Frantz, Aric M., Williams, Christina, Thomas, Rachael, Burnett, Robert C., Avery, Anne C., Breen, Matthew, Mason, Nicola J., O’Brien, Timothy D., Modiano, Jaime F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727651/
https://ncbi.nlm.nih.gov/pubmed/22229753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2011.654337
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