Exome sequencing and the genetic basis of complex traits

Exome sequencing is emerging as a popular approach to study the effect of rare coding variants on complex phenotypes. The promise of exome sequencing is grounded in theoretical population genetics and in empirical successes of candidate gene sequencing studies. Many projects aimed at common diseases...

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Bibliografische gegevens
Hoofdauteurs: Kiezun, Adam, Garimella, Kiran, Do, Ron, Stitziel, Nathan O., Neale, Benjamin M., McLaren, Paul J., Gupta, Namrata, Sklar, Pamela, Sullivan, Patrick F., Moran, Jennifer L., Hultman, Christina M., Lichtenstein, Paul, Magnusson, Patrik, Lehner, Thomas, Shugart, Yin Yao, Price, Alkes L., de Bakker, Paul I.W., Purcell, Shaun M., Sunyaev, Shamil R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727622/
https://ncbi.nlm.nih.gov/pubmed/22641211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2303
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