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Mechanism-based disease progression modeling of type 2 diabetes in Goto-Kakizaki rats

The dynamics of aging and type 2 diabetes (T2D) disease progression were investigated in normal [Wistar-Kyoto (WKY)] and diabetic [Goto-Kakizaki (GK)] rats and a mechanistic disease progression model was developed for glucose, insulin, and glycosylated hemoglobin (HbA1c) changes over time. The study...

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Bibliografische gegevens
Hoofdauteurs: Gao, Wei, Bihorel, Sébastien, DuBois, Debra C., Almon, Richard R., Jusko, William J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727409/
https://ncbi.nlm.nih.gov/pubmed/21127951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-010-9182-0
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