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TLR-Independent Type I Interferon Induction in Response to an Extracellular Bacterial Pathogen via Intracellular Recognition of Its DNA
Type I interferon (IFN) is an important host defense cytokine against intracellular pathogens, mainly viruses. In assessing IFN production in response to group B streptococcus (GBS), we find that IFN-β was produced by macrophages upon stimulation with both heat-killed and live GBS. Exposure of macro...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3727391/ https://ncbi.nlm.nih.gov/pubmed/19064255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2008.11.002 |
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