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Sensitive isotope dilution liquid chromatography/tandem mass spectrometry method for quantitative analysis of bumetanide in serum and brain tissue

We have developed and validated a simple and sensitive stable isotope dilution liquid chromatography/tandem mass spectrometric (LC-MS/MS) method for the quantification of bumetanide in human serum. Samples were prepared with a simple acetonitrile based protein precipitation. The supernatant was then...

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Detalhes bibliográficos
Main Authors: Li, Yijun, Cleary, Ryan, Kellogg, Mark, Soul, Janet S, Berry, Gerard T., Jensen, Frances E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727383/
https://ncbi.nlm.nih.gov/pubmed/21414852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2011.02.018
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