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Quantification of Galactose-1-Phosphate Uridyltransferase Enzyme Activity by Liquid Chromatography–Tandem Mass Spectrometry

BACKGROUND: The diagnosis of galactosemia usually involves the measurement of galactose-1-phosphate uridyltransferase (GALT) activity. Traditional radioactive and fluorescent GALT assays are nonspecific, laborious, and/or lack sufficient analytical sensitivity. We developed a liquid chromatography–t...

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Detalhes bibliográficos
Main Authors: Li, Yijun, Ptolemy, Adam S., Harmonay, Lauren, Kellogg, Mark, Berry, Gerard T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676861/
https://ncbi.nlm.nih.gov/pubmed/20348403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2009.140459
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