CD28-inducible transcription factor DEC1 is required for efficient autoreactive CD4(+) T cell response

During the initial hours after activation, CD4(+) T cells experience profound changes in gene expression. Co-stimulation via the CD28 receptor is required for efficient activation of naive T cells. However, the transcriptional consequences of CD28 co-stimulation are not completely understood. We per...

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Main Authors: Martínez-Llordella, Marc, Esensten, Jonathan H., Bailey-Bucktrout, Samantha L., Lipsky, Robert H., Marini, Ann, Chen, Jun, Mughal, Mohamed, Mattson, Mark P., Taub, Dennis D., Bluestone, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727315/
https://ncbi.nlm.nih.gov/pubmed/23878307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20122387
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