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Design and Synthesis of Mimics of the T7-loop of FtsZ

[Image: see text] Mimics of the T7-loop of the bacterial cell division protein FtsZ have been designed and synthesized. The design is based on the X-ray co-crystal structure of P. aeruginosa FtsZ:SulA. Fast Rigid Exhaustive Docking (FRED) was employed to select compounds that can mimic the key inter...

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Détails bibliographiques
Auteurs principaux: Sorto, Nohemy A., Painter, Phillip P., Fettinger, James C., Tantillo, Dean J., Shaw, Jared T.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727220/
https://ncbi.nlm.nih.gov/pubmed/23721122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol4010068
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