The Role of PTPN22 C1858T Gene Polymorphism in Diabetes Mellitus Type 1: First Evaluation in Greek Children and Adolescents

Type 1 diabetes mellitus (T1DM) is an autoimmune multifactorial disease. Protein tyrosine phosphatase nonreceptor type 22 (PTPN22) gene encodes lymphoid-specific tyrosine phosphatase (Lyp), an inhibitor of T cell activation. PTPN22 C1858T polymorphism was associated with T1DM in populations of Cauca...

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Bibliographische Detailangaben
Hauptverfasser: Giza, Styliani, Goulas, Antonios, Gbandi, Emmanouela, Effraimidou, Smaragda, Papadopoulou-Alataki, Efimia, Eboriadou, Maria, Galli-Tsinopoulou, Assimina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2013
Schlagworte:
Clinical Study
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727122/
https://ncbi.nlm.nih.gov/pubmed/23936838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/721604
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