Endothelium-dependent relaxations in the aorta from K(2p)6.1 knockout mice

K(2P)6.1 or TWIK-2, a two-pore domain K channel, is an important regulator of cardiovascular function. K(2P)6.1 is highly expressed in vascular smooth muscle and endothelium. Mice (8–12 wk) lacking functional K(2P)6.1 (K(2P)6.1(−/−)) are hypertensive and have enhanced vascular contractility. It is n...

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Detalhes bibliográficos
Main Authors: Lloyd, Eric E., Pandit, Lavannya M., Crossland, Randy F., Marrelli, Sean P., Bryan, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Cardiovascular and Renal Integration
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727024/
https://ncbi.nlm.nih.gov/pubmed/23637138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00126.2013
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