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DISRUPTION OF K(2P)6.1 PRODUCES VASCULAR DYSFUNCTION AND HYPERTENSION IN MICE

K(2P)6.1, a member of the Two-Pore Domain K channel family, is highly expressed in the vascular system; however its function is unknown. We tested the following hypotheses. K(2P)6.1 regulates (1) systemic blood pressure, (2) the contractile state of arteries, (3) vascular smooth muscle cell migratio...

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Detalhes bibliográficos
Main Authors: Lloyd, Eric E., Crossland, Randy F., Phillips, Sharon C., Marrelli, Sean P., Reddy, Anilkumar K., Taffet, George E., Hartley, Craig J., Bryan, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205080/
https://ncbi.nlm.nih.gov/pubmed/21876070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.175349
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