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The role of trigeminal nasal TRPM8-expressing afferent neurons in the antitussive effects of menthol

The cold-sensitive cation channel TRPM8 is a target for menthol, which is used routinely as a cough suppressant and as an additive to tobacco and food products. Given that cold temperatures and menthol activate neurons through gating of TRPM8, it is unclear how menthol actively suppresses cough. In...

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Detalhes bibliográficos
Main Authors: Plevkova, J., Kollarik, M., Poliacek, I., Brozmanova, M., Surdenikova, L., Tatar, M., Mori, N., Canning, B. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727002/
https://ncbi.nlm.nih.gov/pubmed/23640596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01144.2012
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