B. anthracis edema toxin increases cAMP levels and inhibits phenylephrine-stimulated contraction in a rat aortic ring model

B. anthracis edema toxin (ET) and lethal toxin (LT) are each composed of protective antigen (PA), necessary for toxin uptake by host cells, and their respective toxic moieties, edema factor (EF) and lethal factor (LF). Although both toxins likely contribute to shock during infection, their mechanism...

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Hlavní autoři: Li, Yan, Cui, Xizhong, Solomon, Steven B., Remy, Kenneth, Fitz, Yvonne, Eichacker, Peter Q.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2013
Témata:
Integrative Cardiovascular Physiology and Pathophysiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726957/
https://ncbi.nlm.nih.gov/pubmed/23585140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00185.2013
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