Lipopolysaccharide-induced phosphorylation of c-Met tyrosine residue 1003 regulates c-Met intracellular trafficking and lung epithelial barrier function

c-Met, the receptor tyrosine kinase whose natural ligand is hepatocyte growth factor, is known to have a key role in cell motility. We have previously shown that lysophosphatidic acid (LPA) induced a decrease in c-Met activation via serine phosphorylation of c-Met at cell-cell contacts. Here, we dem...

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Главные авторы: Zhao, Yutong, Zhao, Jing, Mialki, Rachel K., Wei, Jianxin, Spannhake, Ernst W., Salgia, Ravi, Natarajan, Viswanathan
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726943/
https://ncbi.nlm.nih.gov/pubmed/23624790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00417.2012
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