Effects of Sildenafil on the Gastrocnemius and Cardiac Muscles of Rats in a Model of Prolonged Moderate Exercise Training

Moderate exercise training improves energetic metabolism, tissue perfusion and induces cardiac and skeletal muscle remodeling. Sildenafil, a potent phosphodiesterase-5 inhibitor used to treat erectile dysfunction, reduces infarct size and increases tissue oxygenation in experimental models of cardio...

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Detalhes bibliográficos
Main Authors: Rinaldi, Barbara, Donniacuo, Maria, Sodano, Loredana, Gritti, Giulia, Signoriello, Simona, Parretta, Elisabetta, Berrino, Liberato, Urbanek, Konrad, Capuano, Annalisa, Rossi, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726744/
https://ncbi.nlm.nih.gov/pubmed/23922868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069954
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