Mitochondrial Dysfunction Promotes Breast Cancer Cell Migration and Invasion through HIF1α Accumulation via Increased Production of Reactive Oxygen Species

Although mitochondrial dysfunction has been observed in various types of human cancer cells, the molecular mechanism underlying mitochondrial dysfunction mediated tumorigenesis remains largely elusive. To further explore the function of mitochondria and their involvement in the pathogenic mechanisms...

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Autors principals: Ma, Jia, Zhang, Qing, Chen, Sulian, Fang, Binbin, Yang, Qingling, Chen, Changjie, Miele, Lucio, Sarkar, Fazlul H., Xia, Jun, Wang, Zhiwei
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726697/
https://ncbi.nlm.nih.gov/pubmed/23922721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069485
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