Mitochondrial Dysfunction Promotes Breast Cancer Cell Migration and Invasion through HIF1α Accumulation via Increased Production of Reactive Oxygen Species

Although mitochondrial dysfunction has been observed in various types of human cancer cells, the molecular mechanism underlying mitochondrial dysfunction mediated tumorigenesis remains largely elusive. To further explore the function of mitochondria and their involvement in the pathogenic mechanisms...

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Detalhes bibliográficos
Main Authors: Ma, Jia, Zhang, Qing, Chen, Sulian, Fang, Binbin, Yang, Qingling, Chen, Changjie, Miele, Lucio, Sarkar, Fazlul H., Xia, Jun, Wang, Zhiwei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726697/
https://ncbi.nlm.nih.gov/pubmed/23922721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069485
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