Comparison between Internalizing Anti-HER2 mAbs and Non-Internalizing Anti-CEA mAbs in Alpha-Radioimmunotherapy of Small Volume Peritoneal Carcinomatosis Using (2) (1) (2)Pb

BACKGROUND AND PURPOSE: We assessed the contribution of antibody internalization in the efficacy and toxicity of intraperitoneal α-radioimmunotherapy (RIT) of small volume carcinomatosis using (212)Pb-labeled monoclonal antibodies (mAbs) that target HER2 (internalizing) or CEA (non-internalizing) re...

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Main Authors: Boudousq, Vincent, Bobyk, Laure, Busson, Muriel, Garambois, Véronique, Jarlier, Marta, Charalambatou, Paraskevi, Pèlegrin, André, Paillas, Salomé, Chouin, Nicolas, Quenet, François, Maquaire, Patrick, Torgue, Julien, Navarro-Teulon, Isabelle, Pouget, Jean-Pierre
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726680/
https://ncbi.nlm.nih.gov/pubmed/23922757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069613
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