HIV-1 Infected Lymphoid Organs Upregulate Expression and Release of the Cleaved Form of uPAR That Modulates Chemotaxis and Virus Expression

Cell-associated receptor for urokinase plasminogen activator (uPAR) is released as both full-length soluble uPAR (suPAR) and cleaved (c-suPAR) form that maintain ability to bind to integrins and other receptors, thus triggering and modulating cell signaling responses. Concerning HIV-1 infection, pla...

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Main Authors: Nebuloni, Manuela, Zawada, Lidia, Ferri, Angelita, Tosoni, Antonella, Zerbi, Pietro, Resnati, Massimo, Poli, Guido, Genovese, Luca, Alfano, Massimo
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726662/
https://ncbi.nlm.nih.gov/pubmed/23923008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070606
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