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The Linker Pivot in Ci-VSP: The Key to Unlock Catalysis
In the voltage-sensitive phosphatase Ci-VSP, conformational changes in the transmembrane voltage sensor domain (VSD) are transduced to the intracellular catalytic domain (CD) leading to its dephosphorylation activity against membrane-embedded phosphoinositides. The linker between both domains is pro...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3726396/ https://ncbi.nlm.nih.gov/pubmed/23922964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070272 |
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