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Changes in codon-pair bias of human immunodeficiency virus type 1 have profound effects on virus replication in cell culture
BACKGROUND: Human immunodeficiency virus type 1 (HIV-1) has a biased nucleotide composition different from human genes. This raises the question of how evolution has chosen the nucleotide sequence of HIV-1 that is observed today, or to what extent the actual encoding contributes to virus replication...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2013
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3726367/ https://ncbi.nlm.nih.gov/pubmed/23885919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-78 |
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