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Transmodulation of BCR Signaling by Transduction-Incompetent Antigen Receptors: Implications for Impaired Signaling in Anergic B Cells()
B cell tolerance can be maintained by functional inactivation, or anergy, wherein B cell Ag receptors (BCR) remain capable of binding Ag, but are unable to transduce signals. Although the molecular mechanisms underlying this unresponsiveness are unknown, some models of B cell anergy are characterize...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3726184/ https://ncbi.nlm.nih.gov/pubmed/11970976 |
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