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Sigma (σ) Receptor Ligand, AC927 (N-Phenethylpiperidine Oxalate), Attenuates Methamphetamine-Induced Hyperthermia and Serotonin Damage in Mice

Methamphetamine interacts with sigma (σ) receptors and AC927, a selective σ receptor ligand, protects against methamphetamine-induced dopaminergic neurotoxicity. In the present study, the effects of AC927 on methamphetamine-induced hyperthermia and striatal serotonergic neurotoxicity were evaluated....

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Detalhes bibliográficos
Main Authors: Seminerio, Michael J., Kaushal, Nidhi, Shaikh, Jamaluddin, Huber, Jason D., Coop, Andrew, Matsumoto, Rae R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726056/
https://ncbi.nlm.nih.gov/pubmed/21130800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2010.11.023
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