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AC927, a σ Receptor Ligand, Blocks Methamphetamine-Induced Release of Dopamine and Generation of Reactive Oxygen Species in NG108-15 Cells

Methamphetamine is a highly addictive psychostimulant drug of abuse that causes neurotoxicity with high or repeated dosing. Earlier studies demonstrated the ability of the selective σ receptor ligand N-phenethylpiperidine oxalate (AC927) to attenuate the neurotoxic effects of methamphetamine in vivo...

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Detalhes bibliográficos
Main Authors: Kaushal, Nidhi, Elliott, Meenal, Robson, Matthew J., Iyer, Anand Krishnan V., Rojanasakul, Yon, Coop, Andrew, Matsumoto, Rae R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286303/
https://ncbi.nlm.nih.gov/pubmed/22101517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.111.074120
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