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CM156, a Sigma Receptor Ligand, Reverses Cocaine-Induced Place Conditioning and Transcriptional Responses in the Brain
Repeated exposure to cocaine induces neuroadaptations which contribute to the rewarding properties of cocaine. Using cocaine-induced conditioned place preference (CPP) as an animal model of reward, earlier studies have shown that sigma (σ) receptor ligands can attenuate the acquisition, expression a...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3726055/ https://ncbi.nlm.nih.gov/pubmed/22234290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2011.12.016 |
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