Reduced thrombin binding and aggregation in Bernard-Soulier platelets.

Platelets from two patients with Bernard-Soulier disease showed a reduction in their ability to bind human thrombin. Thrombin binding studies in the high affinity range showed 1,500 sites for the Bernard-Soulier platelets as against 4,000 for normal controls. However, the dissociation constant was t...

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Argitaratua izan da:	J Clin Invest
Egile Nagusiak:	Jamieson, G A, Okumura, T
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Clinical Investigation 1978
Gaiak:	Research Article
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372601/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/641158/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109000
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