Biological and clinical manifestations of Huntington’s disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data

BACKGROUND: Huntington’s disease (HD) is an autosomal dominant, fully penetrant, neurodegenerative disease that most commonly affects adults in mid-life. Our aim was to identify sensitive and reliable biomarkers in premanifest carriers of mutated HTT and in individuals with early HD that could provi...

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Main Authors: Tabrizi, Sarah J, Langbehn, Douglas R, Leavitt, Blair R, Roos, Raymund A C, Durr, Alexandra, Craufurd, David, Kennard, Christopher, Hicks, Stephen L, Fox, Nick C, Scahill, Rachael I, Borowsky, Beth, Tobin, Allan J, Rosas, H Diana, Johnson, Hans, Reilmann, Ralf, Landwehrmeyer, Bernhard, Stout, Julie C
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725974/
https://ncbi.nlm.nih.gov/pubmed/19646924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1474-4422(09)70170-X
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