Diminished spectrin extraction from ATP-depleted human erythrocytes. Evidence relating spectrin to changes in erythrocyte shape and deformability.

We measured spectrin "extractability" in erythrocytes which were metabolically depleted by incubation at 37 degrees C in plasma or glucose-free buffers. Membranes were extracted with 1 mM EDTA (pH 8, 40 h, 4 degrees C) and analyzed by polyacrylamide gel electrophoresis in sodium dodecyl sulfate. Thi...

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Bibliographic Details

Published in:	J Clin Invest
Main Authors:	Lux, S E, John, K M, Ukena, T E
Format:	Artigo
Language:	Inglês
Published:	American Society for Clinical Investigation 1978
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372597/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/25286/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108996
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