Genome-wide linkage analysis for human longevity: Genetics of Healthy Ageing Study

Clear evidence exists for heritability of human longevity, and much interest is focused on identifying genes associated with longer lives. To identify such longevity alleles, we performed the largest genome-wide linkage scan thus far reported. Linkage analyses included 2118 nonagenarian Caucasian si...

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Autors principals: Beekman, Marian, Blanché, Hélène, Perola, Markus, Hervonen, Anti, Bezrukov, Vladyslav, Sikora, Ewa, Flachsbart, Frederieke, Christiansen, Lene, De Craen, Anton J.M., Kirkwood, Tom B.L., Rea, I. Meave, Poulain, Michel, Robine, Jean-Marie, Stazi, Maria Antonietta, Passarino, Giuseppe, Deiana, Luca, Gonos, Efstathios S., Valensin, Silvana, Paternoster, Lavinia, Sørensen, Thorkild I.A., Tan, Qihua, Helmer, Quinta, Van den Akker, Erik B., Deelen, Joris, Martella, Francesca, Cordell, Heather J., Ayers, Kristin L., Vaupel, James W., Törnwall, Outi, Johnson, Thomas E., Schreiber, Stefan, Lathrop, Mark, Skytthe, Axel, Westendorp, Rudi G.J., Christensen, Kaare, Gampe, Jutta, Nebel, Almut, Houwing-Duistermaat, Jeanine J., Slagboom, P. Eline, Franceschi, Claudio
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725963/
https://ncbi.nlm.nih.gov/pubmed/23286790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12039
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