UGT2B17 Genotype and the Pharmacokinetic Serum Profile of Testosterone during Substitution Therapy with Testosterone Undecanoate. A Retrospective Experience from 207 Men with Hypogonadism

Background: Testosterone (T) is mainly excreted in the urine as testosterone glucuronide (TG). This glucuronidation is partly dependent on the UGT2B17 genotype, and TG excretion is therefore lower in men having the UGT2B17 deletion. However, the possible influence of UGT2B17 genotype on serum T duri...

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Bibliografiske detaljer
Main Authors: Bang, Anne Kirstine, Jørgensen, Niels, Rajpert-De Meyts, Ewa, Juul, Anders
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2013
Fag:
Endocrinology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725801/
https://ncbi.nlm.nih.gov/pubmed/23908645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2013.00094
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