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UGT2B17 Genotype and the Pharmacokinetic Serum Profile of Testosterone during Substitution Therapy with Testosterone Undecanoate. A Retrospective Experience from 207 Men with Hypogonadism

Background: Testosterone (T) is mainly excreted in the urine as testosterone glucuronide (TG). This glucuronidation is partly dependent on the UGT2B17 genotype, and TG excretion is therefore lower in men having the UGT2B17 deletion. However, the possible influence of UGT2B17 genotype on serum T duri...

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Autors principals: Bang, Anne Kirstine, Jørgensen, Niels, Rajpert-De Meyts, Ewa, Juul, Anders
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725801/
https://ncbi.nlm.nih.gov/pubmed/23908645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2013.00094
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