Fisetin inhibits growth, induces G(2)/M arrest and apoptosis of human epidermoid carcinoma A431 cells: Role of mitochondrial membrane potential disruption and consequent caspases activation

Non-melanoma skin cancers (NMSCs) one of the most common neoplasms causes serious morbidity and mortality. Therefore, identification of non-toxic phytochemicals for prevention/treatment of NMSCs is highly desirable. Fisetin (3,3′,4′,7-tetrahydroxyflavone), a dietary flavonoid, present in fruits and...

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Hauptverfasser: Pal, Harish C., Sharma, Samriti, Elmets, Craig A., Athar, Mohammad, Afaq, Farrukh
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725735/
https://ncbi.nlm.nih.gov/pubmed/23800058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/exd.12181
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