Gastroesophageal reflux activates the NF-κB pathway and impairs esophageal barrier function in mice

The barrier function of the esophageal epithelium is a major defense against gastroesophageal reflux disease. Previous studies have shown that reflux damage is reflected in a decrease in transepithelial electrical resistance associated with tight junction alterations in the esophageal epithelium. To...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fang, Yu, Chen, Hao, Hu, Yuhui, Djukic, Zorka, Tevebaugh, Whitney, Shaheen, Nicholas J., Orlando, Roy C., Hu, Jianguo, Chen, Xiaoxin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2013
Schlagworte:
Inflammation/Immunity/Mediators
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725692/
https://ncbi.nlm.nih.gov/pubmed/23639809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00438.2012
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