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Regulatory CD8(+) T cells Associated with Erosion of Immune Surveillance in Persistent Virus Infection Suppress in vitro and have a Reversible Proliferative Defect()

CD4(+) T cell help is critical for CD8(+) T cell memory and immune surveillance against persistent virus infections. Our recent data have showed the lack of CD4(+) T cells leads to the generation of an IL-10 producing CD8(+) T cell population during persistent murine γ-herpesvirus-68 (MHV-68) infect...

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Hlavní autoři: Hu, Zhuting, Zhang, Weijun, Usherwood, Edward J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725594/
https://ncbi.nlm.nih.gov/pubmed/23733872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201773
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