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Inhibition of platelet prostaglandin synthetase by oral aspirin.
Aspirin inhibits platelet function by permanently acetylating the cyclooxygenase that forms prostaglandins. We determined the sensitivity of platelets to aspirin in normal subjects by measuring [3H-acetyl]aspirin-susceptible cyclooxygenase in washed platelets obtained at various times after aspirin...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1978
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372541/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/413839/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108941 |
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