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Inhibition of platelet prostaglandin synthetase by oral aspirin.

Aspirin inhibits platelet function by permanently acetylating the cyclooxygenase that forms prostaglandins. We determined the sensitivity of platelets to aspirin in normal subjects by measuring [3H-acetyl]aspirin-susceptible cyclooxygenase in washed platelets obtained at various times after aspirin...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Burch, J W, Stanford, N, Majerus, P W
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1978
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372541/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/413839/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108941
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